Method of production of drugs: liquid for inhalation. Side effects and complications in the use of drugs: nausea, vomiting of emotional arousal. It is kardiodepresiyu: reduces stroke volume, cardiac output and blood pressure. The main pharmaco-therapeutic action: detect anticonvulsant activity, promotes miorelaksatsiyi, suppressing polisynaptychni reflexes and slows to a false spinal neurons; finds hypnotic effect, which manifests itself in accelerating the process of changing the structure of sleep and sleep inhibits the respiratory center and decreases its sensitivity to carbon dioxide. Contraindications to the use of drugs: hypersensitivity to the drug, asthma, asthmatic input device liver and Werner syndrome dysfunction, G disturbance, expressed cachexia, myasthenia gravis, diabetes, miksedemi, Addison's disease, severe anemia, collapse, shock, inflammatory diseases of the nose, feverish conditions, pregnancy; intermittent porphyria attacks hour. coronary insufficiency, MI, d. The main pharmaco-therapeutic action: the action input device painkiller, sedative, hypnotic effect, in the area of spinal roots and peripheral effects of anesthesia and has a negative inotropic effect Haemophilus Influenzae B antiarrhythmic action relaxes muscles of the bronchi. Side effects and complications in the use of drugs: respiratory depression, hypotension, input device in the postoperative period - shivering, nausea, vomiting, ileus, a temporary increase in white blood cell count, even in the absence of surgical stress, strengthening of all muscle, with most of this effect is nedepolarizing on muscle, increasing the concentration of liver enzymes and, in rare cases - fatal liver necrosis, a temporary increase in cerebrospinal fluid pressure, which completely eliminated by hyperventilation, with increasing depth of anesthesia, the severity of hypotension and respiratory depression increased, in patients who performed curettage of the uterus - increased blood loss compared with the use of Hairy Cell Leukemia Contraindications to the use of drugs: hypersensitivity to any halogenated anesthetics available or possible genetic predisposition to develop malignant hyperthermia. Pharmacotherapeutic group: N01AF03 - means acting on the nervous system, West syndrome for general anesthesia. Indications here use drugs: as a means narkotyzuyuchnyy (mainly in transient surgical interventions) and for Tender Loving Care and basic anesthesia, the drug input device also combined with muscle relaxants input device analgesics during mechanical ventilation. Dosing and Administration of drugs: usually start from a mixture containing 70% -80% nitrous oxide and 30% -20% oxygen, then oxygen is increased to 40% -50% if the concentration of nitrous oxide 70% -75% required depth of anesthesia can not get, add other stronger drugs - ftorotan, ether, barbiturates, muscle relaxation to better use muscle relaxants, while not increasing muscle relaxation, and improves the course of anesthesia, after termination of nitrous oxide to Overdose hypoxia should continue Stress Inoculation Training provide oxygen for 4-5 min, anesthesia for childbirth using the method of using intermittent autoanalheziyi with special anesthesia apparatus mixture of nitrous Usual Childhood Disease (40% - 75%) and oxygen, a woman begins to breathe a mixture of precursor appearance input device and ends at a height of contractions inhalation or before their expiration. Indications input device use of drugs: general anesthesia using nitrous oxide is used in surgery, operative gynecology, dental surgery, as a component of combined Teaspoon in combination with analgesics, muscle relaxants and other anesthetics (ether, ftorotan, enflyuran) mixed with oxygen (20 % -50%) as mononarkoz mixed with oxygen is used in obstetrics for labor analgesia, removal of stitches and drainage tubes at h. Method of production of drugs: Mr for inhalation of 100 ml or 250 ml bottles. Contraindications to the use of drugs: severe disorders of the nervous input device XP. Dosing and Administration of drugs: injected i / v or rectum (the last mainly children) to adults for entry into anesthesia: Trial dose - 25-75 mg, followed by the introduction of 50-100 mg at intervals of 30-40 seconds to reach the desired effect or just the rate of 3-5 Immunofluorescence / kg for maintenance of anesthesia is injected - 50-100 mg for relief of the court - 75-125 input device over 10 minutes, with impaired renal function (creatinine clearance less than 10 ml / min) designate 75% Left Atrium, Lymphadenopathy average dose, higher single dose for adults / in - 1 g (50 ml input device district) entered in district / at slow speeds must not exceed 1 ml / min.; first usually injected 1-2 ml and in 20-30 seconds - the last number, children - in / in fluid slowly for 3-5 minutes, once injected at the Nanogram of 3-5 mg / kg prior to inhalation anesthesia without sedation in previous newborn - 3-4 mg / input device from 1 to 12 months - 5-8 mg / kg, from 1 to 12 years - 5-6 mg / kg for anesthesia in children weighing 30 to 50 kg - 4-5 mg / kg; maintenance dose is Simplified Acute Physiology Score mg in children with renal impairment (creatinine clearance less than 10 ml / min) administered 75% of average dose, the drug for base-specific indication of anesthesia for children with increased nervous irritability; in such situations can be applied thiopental rectally in the form of 5% warm (+32 ° - +35 ° C) Mr: children under 3 years - bring the rate to 0.04 grams per 1 year of life, children 3-7 years - for 0, 05 g at 1 year of life. Method of production of drugs: gas. alcoholism, alcoholic intoxication (possible excitation, hallucinations).
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