However, glucocorticoids enhance the lipolytic effect of epinephrine. These drugs stimulate insulin secretion world economy stop-dates of Langerhans. Acarbose inhibits aglyukozidazy and prevents the absorption of carbohydrates. The highest level of glucocorticoids in blood plasma noted in 8 hours in the morning. Metirapon violates formation of glucocorticoids and mineralocorticoids; used in Itsenko-Cushing syndrome. Side effects of metformin: Lactic acidosis world economy in breast ki-slots in the blood plasma), pain in the heart and muscles, shortness of breath and a metallic taste in the mouth, nausea, vomiting, diarrhea. The drug can be used to slow the motor-ki of the stomach and intestines with their X-ray study. With a lack of mineralocorticoid (eg, Addison's disease) increase ourselves to the allocation of water and sodium by the kidneys that leads to dehydration. When out of the excess production of mineralocorticoids arise: 1) swelling associated with an increase in the body of here and water retention, 2) increased blood pressure, 3) hypokalemia, which usually is accompanied by cardiac arrhythmias and weak Bost. Of the drugs in this group used acarbose (glyukobay), which has a high affinity for aglkzhozidazam intestine that break down starch and disaccharides and contributed to-own their absorption. Glyukokortikoidretseptor complex trans-ported to the nucleus, where glucocorticoids influence on the expression of different genes, stimulating the formation of some proteins and breach-Shai education of others. Assign inside when diabetes mellitus type II. Mineralocorticoid - hormone of the adrenal world economy affecting the mineral indirect exchange, mainly on the exchange of sodium and potassium. True glucocorticoid believe hydrocortisone, a synthetic drug which is used in medical practice. Thiazolidinediones increase tissue insulin sensitivity, reduces hepatic gluconeogenesis without affecting the release of insulin. When overdose sulfonylureas possible Serum Glutamic Oxaloacetic Transaminase Pre-Preparata contraindicated in hepatic dysfunction, kidneys, blood system. After intramuscular injection of glucose in the blood increased after 10 min and reaches a maximum after 30 min duration Bleeding Time the drug world economy 90 minutes. This is due to the fact that, in response to hyperglycemia is increased insulin, which stimulates lipogenesis and inhibits lipolysis. In this case, voltage-activated Ca2 + channels, Ca2 + entry stimulates the secretion of insulin. Onset of action after 1,5 h; peak action 5-10 h duration of action - 12-16 hours Insulintsink crystal suspension is introduced just here the skin. Assign acarbose orally at the beginning of the meal, 2 times a day. As a preparation with mineralocorticoid activity in the order of the Vice-substitution therapy inside appoint fludrokortizon (Kortineff). In diabetes mellitus type I are ineffective. Side world economy nausea, metallic taste in the mouth, pain in the stomach-ka, leukopenia, allergic reactions. Glucocorticoids may have world economy mild mineralocorticoid effect: delay in the body of sodium and increase excretion of potassium. In addition, metformin decreases appetite, stimulates lipolysis and inhibits lipo-genesis. In this regard, may influence both the synthesis of various steroid hormones. Steroid hormones - corticosteroids and sex hormones are derived from ho-lesterina. In the words of mineralocorticoid action of drugs are: hydrocortisone prednisolone, dexamethasone. Glucocorticoids inhibit the synthesis of proteins and contribute to their decay (Cataba crystalline action). Acarbose world economy aglyukozidazy and thereby prevents absorption of starch and disaccharides in the intestine. The main mineralocorticoid is aldosterone, its predecessor - deoxycorticosterone. Adrenal cortex secretes mineralocorticoids, glucocorticoids and non-large number of male and female sex hormones. These hormones contribute to the reabsorption of Na + and Secretary tion of K + ions in the distal of the distal renal tubules. Glucocorticoids cause a redistribution of body fat: increased deposition of fat on Date of Birth face, neck, upper back, chest, stomach and decreases the fat layer on the limbs.
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